Searchable abstracts of presentations at key conferences in endocrinology

ea0035p947 | Steroid metabolism and action | ECE2014

Vitamin D is associated with androgen synthesis in human testicular cells

Hofer Daniela , Munzker Julia , Zachhuber Verena , Stiegler Philipp , Hutz Karla , Zigeuner Richard , Pieber Thomas , Muller Helmut , Obermayer-Pietsch Barbara

Introduction: Testosterone production in male testicular cells is mainly stimulated by LH, secreted by the pituitary. Recent findings have shown significant clinical associations of vitamin D seasonal rhythms and androgens in men (Wehr et al. 2010, Nimptsch et al. 2012). We aimed to elucidate associations of vitamin D and androgen synthesis on a cellular level.Methods: Human primary testicular cells, isolated from testes of braindead donors, and a cell l...